Study Of Calico Cat’s Fur May Help Humans Beat Obesity

The forthcoming key for the obese people in losing their weight is now linked straightaway to the unique chromosome structure of calico cats.

Scientists have discovered that the cats have such idiosyncratic fur coat due to two different color genes factor on their X chromosomes. Calico cats who are identified for sleeping all day and being spoiled by their owners have unusual black and orange patches of fur thanks to arbitrary muzzling of one of those chromosomes in each cell.untitled

Calicos are nearly always female, with the exception in the event of an additional Y mutation on one of the pairs. To yield the pattern, both the sex-linked X-chromosomes come together, insistent out other characters. The result is that the genes yield one phenotype over the other, inhibiting one color from overlooking, for example. This fortitude causes a compromise of both.

Scientists are now looking forward for the same method for human beings.

Elizabeth Smith, researcher from University of California San Francisco said if we comprehend how to just incapacitate one X chromosome, it will pave the way to enlighten the complete manner of epigenetic control for example the gene activity can be inherited minus altering the DNA code.

The scientists looked into exact chromosomes by the help of imaging technology called soft x-ray tomography.
“We obtained high-resolution, 3-dimensional views of the intact nucleus and, by using a prototype cryo fluorescence microscope along with the x-ray microscope, we were able to identify one specific chromosome, the inactive X chromosome of female cells,” Smith said in the release.

Although scientists have known for ages the size and structure of nucleotides, this technology has now empowered them to perceive and isolate the specific parts.

The new technology can also break the cycle of many sex-linked genetic disorders like hemophilia and the dreaded Huntington’s disease from spreading generation to generation.

“A cell’s nucleus contains the genetic code, its DNA. But while the structure of the DNA was determined more than 50 years ago, and we’re rapidly determining the position of specific genes on chromosomes, no one had visualized the DNA within an intact nucleus – an unfixed, hydrated whole cell,” said Smith. “We decided to try.”