Utah People's Post

The Latest News from the Beehive State

Sunday, May 22, 2022
Log in
  • National News
    • Female Caseworker Killed & Doctor Shot in Philadelphia
  • State News
    • Car Chase Leads to Drug Arrest
  • Tech & Science
  • Health
    • How to Prepare For Ticks Season
    • Magical Weight Loss Bean Scam
  • Sports
  • Business
You are here: Home / Health / Boehringer, InterMune Identify Drugs To Slow Incurable Lung Disease

Boehringer, InterMune Identify Drugs To Slow Incurable Lung Disease

May 19, 2014 Posted by Staff

The latest data on a pair of rival therapies for fatal idiopathic pulmonary fibrosis (IPF) came out with a clear proof of their ability to slow down the lung disease leading to a major breakthrough in the treatment of the deadly disease.

Pulmonary fibrosis (PULL-mun-ary fi-BRO-sis) is a disease in which tissue deep in the lungs becomes thick and stiff, or disfigured, over time. The formation of scar tissue is called fibrosis. Sometimes doctors are able to discover the reason of fibrosis. But in most cases, they can’t find a cause. They call these cases IPF.

The drugs, pirfenidone and nintedanib, slow the decline of patients with idiopathic pulmonary fibrosis, the researchers said during a meeting of the American Thoracic Society in San Diego.

Among more than 1,000 patients in the two studies, the drug arms showed a decline in the annual rate of FVC (a standard yardstick called forced vital capacity) decline of 48% and 55. The drug inhibited the tyrosine kinase inhibitors.

At least 80,000 Americans suffer from idiopathic pulmonary fibrosis, which is fatal within three to five years for most patients.

Pirfenidone, the InterMune’s drug showed much better outcome than the sample arm on FVC as well. After a year of therapy, 16.5% of the patients in the drug group showed 10% or greater decline after a year’s therapy in FVC.

446-1-hlight
Experts said that current therapies for IPF can only unsharpen the symptoms of the disease, rather than alter its deadly course.They eyes of large group of investors are there on every step of the IPF race being between these two companies. Boehringer need to overcome some secondary endpoint gaffes, though its drug remains very promising.

In an editorial in The New England Journal of Medicine, Brigham & Women’s Gary Hunninghake also noted that there were some forewarnings to consider.

“Although these results are a major breakthrough for patients with idiopathic pulmonary fibrosis, we should be cautious in extrapolating these findings to patients who fall outside the recruitment criteria for these trials,” Hunninghake wrote. “The studies provide little insight into the use of these drugs in patients with more severe disease (FVC <50% of the predicted value) or with an acute disease exacerbation.”

“The study results provide strong evidence of pirfenidone’s robust treatment effects and augment its already well-established safety and tolerability profile,” sats InterMune CEO Dan Welch. “We currently intend to resubmit the pirfenidone New Drug Application to the U.S. Food and Drug Administration in the coming weeks.”

 

Share this:

  • Tweet
  • Share on Tumblr

Filed Under: Health Tagged With: Boehringer, idiopathic pulmonary fibrosis treatment, InterMune, slow down lung disease

Woman working out at the gym

Just 23% of Americans Are Working Out Enough in Their Spare Time

June 29, 2018 By Amelia Donovan

Poliovirus Therapy Gives Brain Cancer Patients New Hope (Study)

June 29, 2018 By Amelia Donovan

United Airlines airplane

Passenger Mysteriously Dies on United Airlines flight Bound for Boston

June 28, 2018 By Amelia Donovan

Breakfast sandwich

Here Are Some Foods No Nutritionist Would Ever Eat

June 27, 2018 By Amelia Donovan

Poppy flower

UN Warns of Surge in Opium-based Drugs and Cocaine Supply

June 27, 2018 By Amelia Donovan

U.S.-Canada border

French Jogger Detained 2 Weeks for Accidentally Crossing Border

June 26, 2018 By Amelia Donovan

Plus size model

Normalizing Plus Size Could Fuel Obesity Crisis (Study)

June 25, 2018 By Amelia Donovan

Giant manta ray

Unique Manta Ray Nursery Spotted off Texas Coast

June 23, 2018 By Amelia Donovan

The rainbow flag

WHO Scraps Transgenderism from List of Mental Illnesses

June 22, 2018 By Amelia Donovan

456 People Dead at U.K. Hospital after Taking too Many Painkillers

June 21, 2018 By Amelia Donovan

Kenyan girls dancing

Kenyans Facing Poor Nutrition as Supermarket Shopping Is on the Rise

June 20, 2018 By Amelia Donovan

Pages

  • About
  • Contact
  • Privacy Policy GDPR
  • Staff
  • Terms and Conditions

Recent Posts

  • Just 23% of Americans Are Working Out Enough in Their Spare Time
  • Poliovirus Therapy Gives Brain Cancer Patients New Hope (Study)
  • Passenger Mysteriously Dies on United Airlines flight Bound for Boston
  • Here Are Some Foods No Nutritionist Would Ever Eat
  • UN Warns of Surge in Opium-based Drugs and Cocaine Supply
  • French Jogger Detained 2 Weeks for Accidentally Crossing Border
  • Normalizing Plus Size Could Fuel Obesity Crisis (Study)

Related Articles

  • Woman working out at the gym

    Just 23% of Americans Are Working Out Enough in Their Spare Time

    Jun 29, 2018
  • Poliovirus Therapy Gives Brain Cancer Patients New Hope (Study)

    Jun 29, 2018
  • Breakfast sandwich

    Here Are Some Foods No Nutritionist Would Ever Eat

    Jun 27, 2018
  • Normalizing Plus Size Could Fuel Obesity Crisis (Study)

    Jun 25, 2018
  • The rainbow flag

    WHO Scraps Transgenderism from List of Mental Illnesses

    Jun 22, 2018
  • 456 People Dead at U.K. Hospital after Taking too Many Painkillers

    Jun 21, 2018
  • Young woman affected by depression

    If You Have PTSD You Were Likely Abused as a Child

    Jun 19, 2018
  • Obese dog on a leash

    Obese Dogs Can Help Us Better Understand How Obesity Works

    Jun 18, 2018
  • Our Brains Are Craving Combinations of Fats and Carbs (Study)

    Jun 15, 2018
  • Hungry bird with beck open

    Scientists Explain Why We Get ‘Hangry’

    Jun 13, 2018

Categories

  • Business
  • Entertainment
  • Health
  • National News
  • Nature
  • Provo
  • Salt Lake News
  • Science
  • Sports
  • State News
  • Tech & Science
  • Technology
  • Uncategorized
  • West Jordan
  • West Valley City
  • World

Copyright © 2022 utahpeoplespost.com

About · Privacy Policy · Terms of Use · Site Map · Contact